Azithromycin is a macrolide antibiotic. It fights bacterial infections by preventing bacteria from producing proteins necessary for their survival and reproduction.
How Azithromycin Works
Specifically, azithromycin binds to the 50S ribosomal subunit of susceptible bacteria. This binding inhibits peptidyl transferase, a key enzyme in protein synthesis. Without functional proteins, the bacteria cannot grow or multiply, leading to their death.
Target Bacteria
- Haemophilus influenzae Moraxella catarrhalis Streptococcus pneumoniae Chlamydia trachomatis Mycoplasma pneumoniae
Azithromycin’s effectiveness varies depending on the specific bacteria. Laboratory testing may be necessary to confirm susceptibility in certain cases.
Pharmacokinetic Properties
Azithromycin is well absorbed after oral administration. It has a long half-life, allowing for once-daily dosing. It concentrates in tissues, particularly phagocytic cells, enhancing its antimicrobial activity. It’s extensively distributed throughout the body.
This unique pharmacokinetic profile contributes to its clinical utility in treating a range of infections.
Important Considerations
Always consult a healthcare professional before using azithromycin. They can determine the appropriate dosage and ensure it’s safe for you, considering any pre-existing conditions or medications you are taking. Inform your doctor about any allergies or adverse reactions you’ve experienced with antibiotics in the past.
Potential Side Effects
- Nausea Diarrhea Abdominal pain Vomiting
Serious side effects are rare but possible. Seek immediate medical attention if you experience severe allergic reactions or other unusual symptoms.
