Viagra, or sildenafil, works by inhibiting an enzyme called phosphodiesterase-5 (PDE5). This enzyme normally breaks down a molecule called cyclic guanosine monophosphate (cGMP).
CGMP and Blood Vessel Relaxation
Higher levels of cGMP lead to relaxation of the smooth muscles in the blood vessels of the penis. This relaxation allows increased blood flow, resulting in an erection. By blocking PDE5, Viagra allows cGMP levels to remain elevated for longer, facilitating this process.
Specific Actions & Considerations
The increased blood flow is targeted; Viagra doesn’t affect blood vessels throughout the entire body. Sexual stimulation is still necessary to trigger the release of nitric oxide, which initiates the cGMP pathway. Therefore, Viagra enhances, but doesn’t initiate, erectile function. Consult a physician before use, especially if you have underlying health conditions.
Important Note on Dosage
Dosage should always follow a doctor’s instructions. Incorrect dosage can lead to adverse effects. The effectiveness of Viagra can vary depending on individual factors.
