Understanding the Key Differences: Prednisolone and Prednisone

Prednisolone and prednisone are both corticosteroids, but they differ in how your cat’s body processes them. Prednisone requires liver metabolism to become active, converting into prednisolone. Cats with liver problems might not efficiently convert prednisone, leading to less effective treatment. Conversely, prednisolone is already active, bypassing this step. This makes prednisolone often the preferred choice for cats, particularly those with pre-existing liver issues.

Dosage and Administration

Dosage depends entirely on your cat’s specific condition and weight. Your veterinarian will determine the appropriate dose and frequency. Prednisolone is typically administered orally, often mixed with food to improve palatability. Always follow your vet’s instructions precisely; never adjust the dosage without consulting them. Incorrect dosage can lead to serious side effects.

Potential Side Effects

Both medications carry potential side effects, including increased thirst and urination, increased appetite, weight gain, and changes in behavior. More serious side effects are possible but less common. Regular monitoring by your veterinarian is crucial to detect and manage any complications.

Choosing the Right Medication

The decision to use prednisolone or prednisone rests solely with your veterinarian. They will consider your cat’s overall health, including liver function, and the specific condition being treated. Open communication with your vet is vital for optimal treatment and management of potential side effects.