Finasteride works by inhibiting the enzyme 5α-reductase, specifically the type II isoenzyme.
Targeting DHT Production
This enzyme is responsible for converting testosterone into dihydrotestosterone (DHT). DHT is a potent androgen that plays a significant role in male pattern hair loss (androgenetic alopecia).
- By blocking 5α-reductase type II, finasteride reduces DHT levels in the scalp. Lower DHT levels lead to a slowdown in hair follicle miniaturization, promoting hair growth and preventing further hair loss.
Understanding the Impact
The decrease in DHT is not systemic; it’s primarily localized to the scalp. This targeted approach minimizes potential side effects associated with broader DHT reduction.
Specific Effects on Hair Follicles
Reduced DHT interaction with hair follicle receptors. Improved hair follicle growth cycle. Increased hair thickness and density.
Important Considerations
Remember, individual responses to finasteride vary. Consistent use is key for optimal results. Consult a healthcare professional before starting any medication, including finasteride.
Beyond Hair Loss
Finasteride also finds application in treating benign prostatic hyperplasia (BPH), due to its ability to reduce DHT levels in the prostate.
