Accutane, or isotretinoin, works by reducing sebum production, a major contributor to acne. This occurs through its interaction with retinoic acid receptors in sebaceous glands, decreasing the size of these glands and thus significantly lowering oil output. Simultaneously, Accutane slows down the growth of skin cells, preventing pores from becoming clogged with dead skin cells and excess oil – a primary cause of acne breakouts.
Treating Severe Acne
Accutane is primarily indicated for the treatment of severe nodular acne, a form of acne characterized by painful, inflamed, and pus-filled lesions. It’s highly effective where other treatments have failed. This includes cases of cystic acne, characterized by deep, painful cysts that can lead to scarring. Accutane also effectively treats acne conglobata, a severe form often resulting in scarring and disfigurement. It’s not a first-line treatment for mild or moderate acne due to its potential side effects.
Beyond Acne: Other Uses
Beyond severe acne, Accutane finds application in managing certain conditions like severe recalcitrant rosacea (inflammation of the skin) and some cases of hidradenitis suppurativa (a chronic inflammatory skin disease).
