Tetracycline Dosage Adjustments for Children and Specific Populations

Tetracycline dosage for children differs significantly from adult dosages. Always consult a doctor to determine the appropriate dose based on the child’s weight and age. Generally, dosages are calculated in milligrams per kilogram of body weight (mg/kg) per day, divided into multiple doses. Precise calculations require a physician’s expertise.

Adjustments for Renal and Hepatic Impairment

Kidney (renal) and liver (hepatic) problems affect how the body processes tetracycline. Reduced kidney function necessitates dosage reduction to prevent drug accumulation and toxicity. Similarly, liver impairment may necessitate dosage adjustments. A doctor will adjust the dosage based on the severity of the impairment and results from relevant lab tests, such as creatinine clearance for kidney function and liver function tests.

Dosage for Pregnant and Breastfeeding Women

Tetracycline is generally avoided during pregnancy due to potential harm to the developing fetus, particularly affecting bone and teeth development. If absolutely necessary, a physician will carefully weigh risks and benefits and may prescribe an alternative antibiotic. During breastfeeding, tetracycline can be excreted in breast milk. A doctor will assess the risks and benefits before prescribing it to breastfeeding mothers.