Ampicillin trihydrate, the hydrated form, is generally more stable than anhydrous ampicillin, particularly in humid conditions. Proper storage is key for maintaining potency.
Ampicillin Trihydrate Storage
- Store below 25°C (77°F). This helps prevent degradation. Maintain a dry environment. Humidity accelerates decomposition. Protect from light. Exposure to light reduces shelf life. Observe the expiration date printed on the packaging. Discard after expiry.
Ampicillin (Anhydrous) Storage
- Store in a cool, dry place, ideally below 15°C (59°F) for optimal stability. Protect from light and moisture. These factors significantly impact stability. Airtight containers are recommended. This minimizes moisture uptake. Careful handling is necessary to prevent moisture absorption. Use immediately after opening if possible.
The practical difference lies in the susceptibility to moisture. Ampicillin trihydrate’s water molecules offer some inherent protection, allowing for slightly less stringent storage conditions compared to anhydrous ampicillin. However, both forms demand careful attention to maintain potency and efficacy.
Stability Considerations
Reconstituted ampicillin solutions are significantly less stable than the powdered forms. Use these solutions promptly. Temperature fluctuations can accelerate degradation in both forms. Consistent storage temperature is paramount. Proper storage practices significantly extend the useful life of both ampicillin and ampicillin trihydrate.
By following these guidelines, you can ensure the quality and effectiveness of your ampicillin supply.
