Sildenafil interacts with several medications. Always inform your doctor about all medications you take, including over-the-counter drugs and supplements. This ensures your safety and helps avoid potential adverse reactions.
Nitrates: Combining sildenafil with nitrates, commonly used to treat angina (chest pain), can cause a dangerous drop in blood pressure. This combination should be strictly avoided.
Alpha-blockers: These medications, often prescribed for high blood pressure or enlarged prostate, can also lower blood pressure when combined with sildenafil. Your doctor may need to adjust your dosages or choose alternative treatments.
CYP3A4 inhibitors: Medications that inhibit the CYP3A4 enzyme, such as ketoconazole and ritonavir, can increase sildenafil levels in your body, potentially leading to side effects. Your doctor may recommend a lower sildenafil dose.
CYP3A4 inducers: Conversely, medications that induce this enzyme, such as rifampin, can decrease sildenafil’s effectiveness. Dosage adjustments might be necessary.
Other medications: Sildenafil may also interact with other medications, including certain antibiotics, antifungals, and blood thinners. Open communication with your healthcare provider is crucial for managing these interactions safely.
Always seek professional medical advice before combining sildenafil with any other medication. Your doctor can assess your individual health status and determine the safest course of action.
