Prednisone, while helpful for managing COPD exacerbations, carries potential side effects. Short-term use usually involves manageable side effects, but prolonged use increases the risk of serious complications.
Common side effects include increased appetite and weight gain, fluid retention, mood swings, insomnia, and increased blood sugar. These often lessen after stopping the medication.
More serious side effects, especially with long-term use, include osteoporosis (weakening of bones), increased risk of infections, high blood pressure, cataracts, glaucoma, and a heightened risk of developing diabetes or worsening existing diabetes. Increased risk of ulcers and gastrointestinal bleeding is also a concern.
Your doctor should carefully monitor you for these potential side effects. Regular blood tests can help track blood sugar levels, and bone density scans might be recommended if you’re on prednisone for an extended period. Open communication with your doctor about any symptoms is critical for managing these risks.
Consider calcium and vitamin D supplements to mitigate osteoporosis risk. Maintaining a healthy diet and regular exercise are important for overall well-being and may help manage some side effects. Always follow your doctor’s instructions carefully regarding dosage and duration of treatment.
Prednisone should not be stopped abruptly; tapering off under medical supervision is necessary to prevent withdrawal symptoms. Never adjust your dosage without consulting your physician.


