Azithromycin, while generally safe and effective, can cause side effects. Common ones include nausea, diarrhea, and abdominal pain. These usually are mild and resolve without intervention. However, some individuals experience more serious reactions.
Gastrointestinal Issues
Beyond the common nausea and diarrhea, severe vomiting and stomach cramping are possible. If you experience significant gastrointestinal distress, contact your doctor immediately. Rarely, azithromycin can cause pseudomembranous colitis, a severe intestinal inflammation. This requires prompt medical attention.
Allergic Reactions
Azithromycin can trigger allergic reactions ranging from mild skin rashes to severe anaphylaxis. Watch for hives, swelling, difficulty breathing, or dizziness. These are medical emergencies requiring immediate treatment. Prior antibiotic allergies should be reported to your physician before starting azithromycin.
Other Potential Side Effects
Less common but serious side effects include liver problems (indicated by jaundice or dark urine), changes in heart rhythm (palpitations), and hearing loss. Seek medical attention if you experience any unusual symptoms. While rare, these complications require monitoring and management.
Drug Interactions
Azithromycin can interact negatively with other medications. Always inform your doctor about all prescription and over-the-counter drugs, supplements, and herbal remedies you’re taking. This is especially important for medications affecting the heart or liver. Failing to do so may increase the risk of harmful side effects.


