Medical Applications: Dilating Blood Vessels to Relieve Angina

Nitroglycerin, in its medical form, rapidly expands blood vessels. This vasodilation lowers the workload on the heart, providing quick relief from angina pain. The medication achieves this by relaxing the smooth muscles in the artery walls, increasing blood flow and oxygen delivery to the heart muscle.

How Nitroglycerin Works

The process begins with nitroglycerin’s conversion into nitric oxide within the body. Nitric oxide is a powerful signaling molecule that triggers smooth muscle relaxation. This results in wider blood vessels, reduced blood pressure, and decreased cardiac oxygen demand. Consequently, chest pain associated with angina diminishes. Doctors often prescribe nitroglycerin sublingually (under the tongue) for immediate relief, as it absorbs quickly into the bloodstream. Transdermal patches provide sustained-release treatment for ongoing angina management.

Dosage and Administration

Dosage varies depending on individual needs and severity of angina. Always follow your doctor’s instructions precisely. Incorrect usage can lead to side effects like headaches, dizziness, or low blood pressure. Seek immediate medical attention if you experience severe side effects or if your angina pain persists despite taking nitroglycerin.