Long-Term Effects and Potential Complications: What are the Long-Term Implications?

Regular monitoring is key. Your doctor should regularly check your blood glucose, weight, and liver function. This helps catch potential problems early.

Weight gain is a common side effect. Maintaining a healthy diet and exercise routine can help mitigate this.

Fluid retention (edema) can occur. This is often manageable with lifestyle changes and, in some cases, medication adjustments.

Heart failure risk may increase, particularly in patients with pre-existing conditions. Open communication with your physician is crucial for risk management.

Fracture risk may also increase. Discuss bone density testing and preventative measures with your doctor.

Bladder cancer risk is slightly elevated. This risk is generally low, but regular checkups are important.

Liver problems are a possibility. Your doctor will conduct liver function tests to assess your risk and monitor for abnormalities.

Discontinue pioglitazone immediately if you experience any concerning symptoms like severe abdominal pain, jaundice, or unusual fatigue. Contact your healthcare provider promptly.

The long-term benefits of pioglitazone need to be weighed against these potential risks. Your doctor can help you make an informed decision based on your individual health profile.