Interactions with Other Medications and Substances

Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal remedies, and supplements. This includes nitrates (used to treat chest pain), alpha-blockers (for high blood pressure or enlarged prostate), and certain antifungals.

Specific interactions can significantly affect Tadalafil’s performance and potentially cause adverse effects. Here’s a breakdown:

    Nitrates: Combining Tadalafil with nitrates can cause a dangerous drop in blood pressure. This combination is strictly contraindicated. Alpha-blockers: Concurrent use may lead to a significant drop in blood pressure, especially upon standing. Your doctor might adjust your dosages or suggest alternative treatments. Antifungal medications (like ketoconazole and itraconazole): These can increase Tadalafil levels in your body, potentially intensifying side effects. Dosage adjustment may be necessary. HIV protease inhibitors: These medications can also increase Tadalafil blood levels, requiring careful monitoring and potential dosage reduction. Grapefruit juice: Avoid grapefruit juice as it can interfere with Tadalafil’s metabolism, increasing its concentration in your blood.

Alcohol can amplify Tadalafil’s side effects, particularly dizziness and lightheadedness. Moderate alcohol consumption is generally advised, but consult your doctor for personalized guidance.

This information is not exhaustive. Consult your physician or pharmacist for a complete list of potential interactions and for personalized advice based on your specific health conditions and medications.