Always inform your doctor about all medications you’re taking, including over-the-counter drugs, supplements, and herbal remedies, before starting nabumetone. This includes aspirin and other NSAIDs.
Lithium: Nabumetone can increase lithium levels in your blood. Your doctor might need to adjust your lithium dosage to prevent toxicity. Regular blood tests will monitor your lithium levels.
Blood thinners (anticoagulants): Nabumetone may increase the risk of bleeding when used with warfarin or other anticoagulants. Close monitoring of your blood clotting time is necessary. Your doctor might need to adjust your dosage of the anticoagulant.
Diuretics: Combining nabumetone with diuretics might reduce the effectiveness of the diuretic. Your doctor may monitor your blood pressure and adjust your medication accordingly.
ACE inhibitors and ARBs: Nabumetone may reduce the effectiveness of these blood pressure medications. Your blood pressure needs careful monitoring.
Methotrexate: Concurrent use increases the risk of methotrexate toxicity. Close monitoring is crucial. Dosage adjustments may be required.
Cyclosporine: Increased risk of kidney problems exists with concurrent use. Regular kidney function tests are necessary.
This information is not exhaustive. Consult your doctor or pharmacist for a complete list of potential interactions and for personalized advice on managing your medications safely.
