Metformin, while generally well-tolerated, commonly causes gastrointestinal upset. About 20% of patients experience diarrhea, which may be mild and resolve spontaneously within a few weeks. Nausea is another frequent complaint, often accompanied by a metallic taste. Abdominal cramping and bloating are also relatively common side effects. These symptoms usually improve if you take metformin with food, particularly a meal higher in protein and fiber. Gradual dose escalation can also help minimize gastrointestinal discomfort. If symptoms persist or worsen despite these measures, speak to your doctor; they might recommend a different medication or a lower dosage.
Less common, but still possible, are more severe gastrointestinal issues. These can include vomiting and significant weight loss. These symptoms should be reported immediately to your physician. They may indicate a serious problem requiring medical attention.
To manage milder gastrointestinal effects, consider these tips: Take metformin with a full glass of water, avoid alcohol, and maintain adequate hydration. Dietary changes, like reducing consumption of high-fat foods or simple sugars, can also prove beneficial. Finally, consistent monitoring of bowel habits is useful in tracking any changes or persistent problems.


