Avoid taking acetazolamide with lithium. This combination can significantly increase lithium levels, leading to lithium toxicity. Monitor your lithium levels closely if you must use both medications.
Combining acetazolamide and potassium-sparing diuretics (like amiloride or spironolactone) increases the risk of hyperkalemia (high potassium levels in the blood). Regular potassium level monitoring is crucial if this combination is unavoidable.
Acetazolamide can interact with medications metabolized by the liver, potentially affecting their effectiveness or causing increased side effects. Consult your doctor before combining acetazolamide with other medications, especially those known to affect liver enzymes.
Concurrent use of acetazolamide and nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the effectiveness of acetazolamide in treating glaucoma. This combination requires close monitoring of intraocular pressure.
Taking acetazolamide with medications that cause metabolic acidosis increases the risk of severe acidosis. This includes some antiretroviral medications. Your physician should assess potential risks before prescribing both.
Be sure to inform your doctor or pharmacist of all medications, including over-the-counter drugs and supplements, you are currently taking before starting acetazolamide treatment. This includes herbal remedies. Open communication is paramount for your safety.
