Avoid prednisolone if the patient has an active peptic ulcer or untreated infections. These conditions worsen with steroid use.
Carefully monitor blood glucose levels. Prednisolone can elevate blood sugar, potentially necessitating adjustments to diabetes medications.
Closely observe for signs of increased intraocular pressure. Prednisolone can exacerbate glaucoma. Regular eye examinations are recommended.
Assess for signs of fluid retention. Prednisolone can cause sodium and water retention, potentially exacerbating ascites. Regular monitoring of weight and abdominal girth is crucial.
Monitor for signs of infection. Prednisolone suppresses the immune system, increasing susceptibility to infections. Prompt treatment of any infection is paramount.
Use caution in patients with hypertension. Prednisolone can further increase blood pressure. Regular blood pressure monitoring is necessary.
Taper prednisolone dosage gradually upon discontinuation to prevent adrenal insufficiency. Sudden cessation can lead to serious complications.
Regularly monitor liver function tests. Prednisolone can affect liver function, particularly in patients with pre-existing cirrhosis.
Patients should be advised about potential side effects, including mood changes, insomnia, and increased risk of osteoporosis. Patient education is vital for successful management.
Consider alternative therapies if the risks outweigh the potential benefits. The clinical picture and patient’s overall health must inform treatment decisions.
