Amiloride HCTZ 5/50 mg tablets combine a potassium-sparing diuretic (amiloride) with a thiazide diuretic (hydrochlorothiazide). This combination effectively manages fluid retention and high blood pressure. The primary use is treating hypertension (high blood pressure), often in patients who require additional control beyond what a thiazide diuretic alone provides.
Managing Hypertension
Amiloride HCTZ 5/50 mg helps lower blood pressure by increasing the excretion of sodium and water from the body. Amiloride’s potassium-sparing action helps prevent the potassium loss that can occur with thiazide diuretics alone, reducing the risk of hypokalemia (low potassium levels). This combination is particularly useful for patients whose blood pressure isn’t adequately controlled by a thiazide diuretic alone or those at risk of developing hypokalemia.
Treating Edema
This medication also finds use in managing edema (fluid retention) associated with various conditions, such as heart failure or cirrhosis. The diuretic effect promotes fluid loss, reducing swelling in the extremities and improving symptoms. Always follow your doctor’s instructions regarding dosage and duration of treatment.


