Elderly patients taking amoxicillin may experience digestive issues like diarrhea or nausea. These are often mild and resolve without intervention, but persistent or severe symptoms require medical attention. Dehydration is a particular concern for older adults, so ensure adequate fluid intake.
Gastrointestinal Effects
Amoxicillin can disrupt the gut’s natural bacteria, potentially leading to a yeast infection (candidiasis), manifesting as oral thrush or vaginal yeast infections. Report any unusual vaginal discharge or mouth sores to your doctor immediately. Consider probiotic supplements to help restore gut health, but consult your physician before starting any new supplements.
Allergic Reactions
While rare, allergic reactions can be severe. Watch for symptoms such as skin rash, hives, itching, swelling of the face, lips, or tongue, difficulty breathing, or dizziness. Seek immediate medical care if an allergic reaction occurs. A previous penicillin allergy increases the risk; always inform your doctor of any past allergic reactions to antibiotics.
Drug Interactions
Amoxicillin can interact with certain medications. For example, it may reduce the effectiveness of oral contraceptives. Always provide your doctor with a complete list of all medications, including over-the-counter drugs and supplements, you are currently taking. This helps prevent potential interactions.
Monitoring and Dosage Adjustments
| Kidney function | Reduced kidney function is common in older adults. Your doctor will likely adjust the amoxicillin dose based on your creatinine clearance to prevent drug accumulation. Regular monitoring of kidney function is recommended during treatment. |
| Liver function | Amoxicillin is mostly processed by the kidneys, but liver problems can affect its metabolism. Your doctor may order liver function tests, especially if you have a history of liver disease. |
| Other medications | Regular review of all medications helps identify and manage potential drug interactions. |
Monitoring for Adverse Events
Regular check-ups allow doctors to monitor for any side effects and make necessary adjustments to treatment. Don’t hesitate to contact your doctor if you experience any unusual symptoms or side effects. Open communication ensures optimal treatment and patient safety.


