Prednisone often leads to fat redistribution, meaning weight gain isn’t evenly distributed. You might notice increased fat around your abdomen, creating a characteristic “moon face” appearance.
Another common area is the upper back and neck. This fat accumulation can lead to a “buffalo hump” – a significant buildup of fat between the shoulders.
Weight gain also frequently affects the arms and thighs, though the accumulation may be less pronounced than in the abdominal area or upper back.
Keep in mind that individual responses vary. While these areas are frequently affected, your personal experience might differ.


