Consult eMedicine for detailed prescribing information, including dosage adjustments for renal and hepatic impairment. Always verify this information with your local drug formulary.
Augmentin, a combination of amoxicillin and clavulanate potassium, combats bacterial infections by inhibiting bacterial cell wall synthesis. Clavulanate protects amoxicillin from beta-lactamase enzymes, broadening its effectiveness against resistant strains.
Common uses include respiratory tract infections like pneumonia and bronchitis, skin and soft tissue infections, urinary tract infections, and otitis media. However, appropriate antibiotic stewardship dictates careful consideration of local resistance patterns before prescribing.
Side effects range from mild gastrointestinal upset (diarrhea, nausea) to more serious allergic reactions. Patients with penicillin allergies require special caution. Monitor for signs of Clostridium difficile-associated diarrhea.
Dosage varies based on infection severity, patient weight, and renal function. Always follow prescribed guidelines and duration of treatment. Premature discontinuation may lead to treatment failure and the development of resistant bacteria.
Drug interactions are possible; consult eMedicine’s detailed drug interaction database for a complete list. Specific attention should be paid to interactions with oral contraceptives and anticoagulants.
For children, Augmentin suspension offers convenient administration. Properly measure doses using the provided measuring device to ensure accurate administration. Adhere to proper storage instructions for optimal efficacy.
Remember: This information serves as a general overview. Always consult eMedicine and other authoritative sources for complete and up-to-date prescribing information. Individual patient circumstances will always dictate specific treatment plans.
