Atorvastatin calcium is the salt form of atorvastatin. This means it’s atorvastatin bound to a calcium ion. The calcium ion improves the drug’s solubility and absorption in the body. This difference is significant only in formulation and administration; therapeutically, both forms deliver the same active ingredient – atorvastatin.
Pharmacokinetic Differences
While both drugs contain the same active ingredient, the calcium salt generally leads to higher bioavailability. This means a larger proportion of the administered dose reaches the bloodstream, requiring potentially smaller dosages to achieve therapeutic effects. Specific absorption rates will vary based on the formulation and individual patient factors.
Clinical Implications
Clinicians prescribe either form interchangeably, depending on the specific drug preparation available. Patients should not experience any difference in treatment efficacy provided dosage is adjusted appropriately if switching between atorvastatin and atorvastatin calcium preparations. Always follow your doctor’s prescribed dosage and instructions.
Choosing Between Forms
The choice between atorvastatin and atorvastatin calcium often comes down to formulation and cost. Generic formulations of either form are widely available, and price comparisons may influence the physician’s choice. The therapeutic efficacy remains the same regardless of the chosen form.
