Aciclovir remains a first-line treatment for initial and recurrent herpes simplex virus (HSV) infections, including oral and genital herpes. It’s also effective against varicella-zoster virus (VZV), causing chickenpox and shingles. Doctors typically prescribe aciclovir for mild to moderate cases.
Aciclovir’s Strengths
Aciclovir’s advantages include its widespread availability, generally good tolerability, and relatively low cost. It’s generally safe for most adults and children, making it a suitable option for many patients. For recurrent HSV outbreaks, prophylactic aciclovir can significantly reduce frequency and severity.
When to Consider Alternatives
Valaciclovir, a prodrug of aciclovir, offers improved bioavailability, meaning a higher concentration of the active drug reaches the bloodstream with a lower dose. This is beneficial for patients who struggle with swallowing pills or require faster symptom relief. Famciclovir, another antiviral, is also effective against HSV and VZV, offering similar benefits to valaciclovir. For severe or complicated cases of HSV or VZV infections, or if aciclovir proves ineffective, a physician might opt for stronger antiviral medications. These include foscarnet or cidofovir, used particularly for cases of resistant viruses.
Choosing the Right Treatment
The choice between aciclovir and other antivirals depends on individual patient factors, including the severity of the infection, the patient’s medical history, and any potential drug interactions. A healthcare professional should carefully assess these factors to determine the most appropriate treatment strategy. Always consult your doctor before starting any antiviral medication.
